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Copper(I) bromide catalyzed arylation of cyclic enamides and naphthyl-1-acetamides using diaryliodonium salts
Muthuraj Prakash, Subramaniam Muthusamy,
Published in American Chemical Society
2014
PMID: 25111372
Volume: 79
   
Issue: 17
Pages: 7836 - 7843
Abstract
Copper(I) bromide catalyzed direct C-H arylation of cyclic enamides was achieved using diaryliodonium salts in the absence of base/additive at ambient temperature with high yields. A biologically active dihydro[a]benzocarbazole scaffold was synthesized using the established protocol. The scope of the current methodology was further extended for the synthesis of C4-, C7-aryl-substituted 1-naphthyl acetamides in good yields. © 2014 American Chemical Society.
About the journal
JournalData powered by TypesetJournal of Organic Chemistry
PublisherData powered by TypesetAmerican Chemical Society
ISSN00223263
Open AccessNo
Concepts (33)
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    Aromatic compounds
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    Catalysis
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    Chemical reactions
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    Salts
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    Scaffolds
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    ARYLATIONS
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    BENZOCARBAZOLE
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    C-H ARYLATION
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    COPPER BROMIDE
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    DIARYLIODONIUM SALTS
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    ENAMIDES
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    High yield
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    Copper
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    Acetamide derivative
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    Bromine derivative
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    COPPER(I) BROMIDE
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    Cuprous ion
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    DIARYLIODONIUM SALTS
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    Inorganic salt
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    NAPHTHYL 1 ACETAMIDE
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    Unclassified drug
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    Carbazole derivative
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    Alkylation
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    Article
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    Arylation
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    Cyclization
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    Environmental temperature
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    Synthesis
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    Chemical structure
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    Chemistry
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    Acetamides
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    Carbazoles
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    Molecular structure