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Statistical optimization of production medium for β-1,3-glucanase synthesis by Trichoderma harzianum
Kalaimahan Théodore,
Published in Kluwer Academic Publishers
Volume: 8
Issue: 6
Pages: 381 - 384
Response surface methods were used to determine the optimum concentration of medium nutrients for extracellular β-1,3-glucanase production by Trichoderma harzianum in shakeflask culture. A Plackett-Burman design was used to screen the important variables which were then grouped and studied by a central composite design. The optimum levels of the medium constituents were determined by the complex algorithm of Box. © 1994 Chapman & Hall, London.
About the journal
JournalBiotechnology Techniques
PublisherKluwer Academic Publishers
Open AccessNo