In this endeavor, the transients persisting in a vacuum ejector system are studied by numerically simulating the flowfield and experimentally validating the steady-state results. An inertial effect is discovered in the study due to the recirculation zone moving forward and backward during the transients, and subsequently the pressure in the secondary chamber oscillates. The flow exhibits damped oscillations in which the direction of the mass flux through the secondary chamber keeps changing and finally settles downtoastateinwhich thereisnomass flux intoorfrom the secondary chamber.It isseen that the characteristics ofthe short transientsin pressure and mass fluxinthe secondary chamber depend highlyonthe thicknessesof the primary and secondary jets and the secondary chamber volume. The inertial effect reduces with the reduction in thicknesses of both primary and secondary jets. As the volume of the secondary chamber increases, the inertial effect decreases further. It is also seen that the inertial effect decreases as the primary jet pressure increases, while other parameters remain constant. The movement of the recirculation zone during these initial transients is also studied in detail and found to be closely related to the mentioned ejector parameters. Copyright © 2014 by the American Institute of Aeronautics and Astronautics, Inc.