This paper reports a study of heat transfer in the post-critical heat flux (post-CHF) regime under forced convective upflow conditions in a uniformly heated vertical tube of 12.7 mm internal diameter and 3 m length. Experiments were conducted with non-azeotropic ternary refrigerant mixture R-407C for reduced pressures ranging from 0.37 to 0.75, mass flux values from 1200 to 2000 kg/m2 s and heat flux from 50 to 80 kW/m2. Data shows a considerable effect of system pressure on the post-CHF heat transfer coefficient for specified mass and heat fluxes. The post-CHF heat transfer coefficients for R-407C are compared with three existing correlations which are found to over predict the current data. A modified correlation to represent the experimental data for R-407C is presented. © 2009 Elsevier Ltd. All rights reserved.