Get all the updates for this publication
Articles
N-substituted 1,2-dihydroquinolines as anticancer agents: Electronic control of redox stability, assessment of antiproliferative effects, and mechanistic insightsPublished in
2013
PMID: 23918415
Volume: 8
Issue: 10
Pages: 1623 - 1628
[No abstract available]
Content may be subject to copyright.
Related Papers (3)
About the journal
| Journal | ChemMedChem |
|---|---|
| ISSN | 18607179 |
| Open Access | No |
Authors (2)
Kannoth Manheri Muraleedharan- 1-Hydroxymethyl-7-oxabicyclo[2.2.1]hept-2-ene skeleton in enantiopure form through enzymatic kinetic resolution
- Broad spectrum anti-infective properties of benzisothiazolones and the parallels in their anti-bacterial and anti-fungal effects
- Trans -β2,3-amino acid-based supramolecular synthons for probing the interrelationships between structure, torsion-directed assembly, and isomorphism
- A modular approach towards drug delivery vehicles using oxanorbornane-based non-ionic amphiphiles
Devarajan Karunagaran- The flavonoid quercetin induces cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells through p53 induction and NF-κB inhibition
- Menadione (Vitamin K3) induces apoptosis of human oral cancer cells and reduces their metastatic potential by modulating the expression of epithelial to mesenchymal transition markers and inhibiting migration
- Three dimensional structure of the closed conformation (active) of human merlin reveals masking of actin binding site in the FERM domain
- Quercetin attenuates Monocyte Chemoattractant Protein-1 gene expression in glucose primed aortic endothelial cells through NF-κB and AP-1
Concepts (52)
1 (3 HYDROXY 1 METHOXY 1 OXOPROPAN 2 YL) 6 NITRO 1,2 DIHYDROQUINOLINE 3 CARBOXYLATE- 6 NITRO 1 (1 PHENYLETHYL) 1,2 DIHYDROQUINOLINE 3 CARBOXYLATE
- Acetic acid derivative
- Alkyl group
- Amine
- ANTIINFLAMMATORY AGENT
- Antineoplastic agent
- Ascorbic acid
- Ester
- GLUCOCORTICOID RECEPTOR
- Hydrogen
- MENADIONE
- Nitrogen
- Quinoline derivative
- Quinone derivative
- Reactive oxygen metabolite
- Rna directed dna polymerase
- Unclassified drug
- Acylation
- Antiproliferative activity
- Apoptosis
- Article
- Baylis hillman reaction
- Cell proliferation
- Controlled study
- Cytotoxicity
- Drug synthesis
- Electron transport
- Human
- Human cell
- Lipid peroxidation
- Mitochondrial membrane potential
- Oxidation
- Priority journal
- Chemistry
- Drug effects
- G2 phase cell cycle checkpoint
- Hela cell line
- M phase cell cycle checkpoint
- Metabolism
- Oxidation reduction reaction
- Synthesis
- Tumor cell line
- Antineoplastic agents
- Cell line, tumor
- G2 PHASE CELL CYCLE CHECKPOINTS
- Hela cells
- Humans
- M PHASE CELL CYCLE CHECKPOINTS
- Oxidation-reduction
- Quinolines
- Reactive oxygen species
