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Enantiospecific synthesis of ABC-ring system of A-nor and abeo 4(3→2) tetra and pentacyclic triterpenes
, A. Srikrishna, R. Ramesh Babu
Published in Elsevier BV
2010
Volume: 66
   
Issue: 4
Pages: 852 - 861
Abstract

Enantiospecific synthesis of ABC-ring systems of A-nor and abeo 4(3→2) tetra and pentacyclic triterpenes has been accomplished starting from the readily available monoterpene (R)-carvone. (R)-Carvone was used as the B-ring of the target molecules. A lithium-liquid ammonia mediated cyclisation of δ,ɛ-unsaturated ester was employed for the cyclopentannulation at the C-5 and C-6 carbons of carvone and an RCM reaction was employed for the cyclohexannulation to generate the ABC-ring system of A-nor tetra and pentacyclic triterpenes. The strategy has been extended for the synthesis of the ABC-ring system of abeo 4(3→2) tetra and pentacyclic triterpenes.

About the journal
JournalData powered by TypesetTetrahedron
PublisherData powered by TypesetElsevier BV
Open AccessNo