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An enantiospecific synthesis of (−)-2-hydroxy-exo-brevicomin was achieved from l-(+)-tartaric acid in high yield. The key step involves a very highly diastereoselective reduction of a keto Weinreb amide.
Journal | Data powered by TypesetTetrahedron: Asymmetry |
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Publisher | Data powered by TypesetElsevier BV |
Open Access | No |