Atomically precise noble metal nanoclusters (NCs) are an important class of emerging materials. Their novel properties have made them an indispensable material for understanding structure-property correlation at the nanoscale. Precise determination of the atomic structure of NCs becomes vital in this respect. There is an apparent necessity for looking beyond SCXRD to understand the structural details of NCs. Recent advancements have shown that electron microscopy can be an effective technique to address many of these issues. This chapter will discuss significant advancements concerning understanding NCs and imaging them using electron microscopy, and briefly on other related techniques. © 2023 Elsevier Inc. All rights reserved.