Header menu link for other important links
Diastereoselective Palladium Catalyzed Carbenylative Amination of ortho ‐Vinylanilines with 3‐Diazoindolin‐2‐ones
, Chandra Shekar Reddy Angula, Maheswar Reddy Palagulla
Published in Wiley
Volume: 362
Issue: 4
Pages: 801 - 806

A diastereoselective palladium catalyzed carbenylative amination of ortho-vinylaniline with 3-diazoindolines-2-one have been accomplished for the synthesis of various tetrasubstituted indoline fused spirooxindole with good yields and diastereoselectivity. Notable features of the method include construction of two contiguous tetrasubstituted carbon stereocenters via C−N and C−C bond formation in single operation, wide functional group tolerance and high atom and step economy. Importantly, the present reaction was also extended to one-pot conversion of tosylhydrazones and ortho-vinylanilines to spirooxindole derivatives.

About the journal
JournalData powered by TypesetAdvanced Synthesis & Catalysis
PublisherData powered by TypesetWiley
Open AccessNo