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A series of highly efficient and inexpensive bioxazoline ligands were easily synthesized from tartaric acid and further explored for enantioselective addition of terminal alkynes to imines in combination with copper(II) salts. This is the first ever report showing application of bidentate bioxazoline ligands in the synthesis of propargylamines with good enantioselectivity.
Journal | Data powered by TypesetTetrahedron Letters |
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Publisher | Data powered by TypesetElsevier BV |
ISSN | 0040-4039 |
Open Access | No |