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Tuning nano electric field to affect restrictive membrane area on localized single cell nano-electroporationPublished in
2013
DOI: 10.1063/1.4833535
Volume: 103
Issue: 23
Interaction of electric field with biological cells is an important phenomenon for field induced drug delivery system. We demonstrate a selective and localized single cell nano-electroporation (LSCNEP) by applying an intense electric field on a submicron region of the single cell membrane, which can effectively allow high efficient molecular delivery but low cell damage. The delivery rate is controlled by adjusting transmembrane potential and manipulating membrane status. Thermal and ionic influences are deteriorated from the cell membrane by dielectric passivation. Either reversible or irreversible by LSCNEP can fully controlled with potential applications in medical diagnostics and biological studies. © 2013 AIP Publishing LLC.
Topics: Membrane potential (52)%52% related to the paper, Cell membrane (51)%51% related to the paper and Membrane (51)%51% related to the paper
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Content may be subject to copyright.This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publ... ...This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in [Tuning nano electric field to affect restrictive membrane area on localized single cell nano-electroporation. Applied Physics Letters 103, 23 p233701 (2013)] and may be found at https://doi.org/10.1063/1.4833535.
About the journal
| Journal | Applied Physics Letters |
|---|---|
| ISSN | 00036951 |
| Open Access | No |
Authors (1)
Tuhin Subhra Santra- Pulse laser activated photoporation for high efficient intracellular delivery using nano-corrugated mushroom shape gold nanoparticles
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