Kalapattukuppuswamy Kuppuswamy B. Balasubramanian

S. Selvaraj

IIT Madras is a public technical and research university located in Chennai, Tamil Nadu. Founded in 1959, it is recognised as an Institute of National Importance.

IIT Madras has been ranked as the top engineering institute in India for four years in a row by the National Institutional Ranking Framework of the MHRD

It currently offers undergraduate, postgraduate and research degrees across 16 disciplines in Engineering, Sciences, Humanities and Management. About 596 faculty belonging to science and engineering departments and centres of the Institute are engaged in teaching, research and industrial consultancy.

IIT Madras

Synthesis (Germany)

The [2+2+2] cycloaddition strategy is complementary to the well known Diels-Alder reaction for the generation of polycyclic compounds. This [2+2+2] approach is atom-economical and, with the availability of new catalysts to effect the [2+2+2] cycloaddition reaction, synthesis of a wide variety of highly functionalized polycycles is possible. This review deals with some recent advances relating to [2+2+2] cycloaddition reactions involving the syntheses both of polycycles and of heterocycles. More specifically, syntheses of various biologically active molecules, unusual amino acids, and theoretically interesting molecules are described. An attempt has also been made to give an overview of recent advances in the achievement of chemo-, regio-, and stereoselectivity in cyclotrimerization reactions. © Wiley-VCH Verlag GmbH & Co. KGaA, 2005.

Journal	Synthesis (Germany)
Publisher	Georg Thieme Verlag
ISSN	00397881
Open Access	No