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The effect of oxidation on the mechanical response of isolated elastin and aorta
Published in American Society of Mechanical Engineers (ASME)
2019
PMID: 30942830
Volume: 141
   
Issue: 6
Abstract
Oxidation of aorta by hydroxyl radicals produces structural changes in arterial proteins like elastin and collagen. This in turn results in change in the mechanical response of aorta. In this paper, a thermodynamically consistent constitutive model is developed within the framework of mixture theory, to describe the changes in aorta and isolated elastin with oxidation. The model is then studied under uniaxial extension using experimental data from literature. © 2018 ASME. All rights reserved.
About the journal
JournalJournal of Biomechanical Engineering
PublisherAmerican Society of Mechanical Engineers (ASME)
ISSN01480731
Open AccessNo
Concepts (27)
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    Aging of materials
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    ELASTIN
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    Glycoproteins
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    Mixtures
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    Oxidation
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    Aorta
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    HYDROXYL RADICALS
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    Mechanical response
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    MIXTURE THEORY
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    UNIAXIAL EXTENSION
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    Blood vessels
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    ELASTIN
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    Aging
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    Animal tissue
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    Article
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    Chemical reaction kinetics
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    Controlled study
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    Energy balance
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    Genetic algorithm
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    KINEMATICS
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    Mechanics
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    Nonhuman
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    Oxidation kinetics
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    PROTEIN CONTENT
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    Reaction analysis
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    Stoichiometry
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    Thermodynamics