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Synthesis of Unsymmetrical Linear Diarylheptanoids and their Enantiomers and Antiproliferative Activity Studies
Kasireddy Sudarshan, Govindaraj Perumal, ,
Published in Wiley-VCH Verlag
Volume: 2018
Issue: 45
Pages: 6379 - 6387
Successful synthesis of unsymmetrical linear diarylheptanoids with syn-1,3-diol unit and their enantiomers have been achieved using acyl anion and Wittig olefination chemistry. The syn disposition of the two hydroxyl groups in the linear diarylheptanoids was achieved with the use of d-xylose as starting material. The synthesized compounds were tested for anti-proliferative activity on HeLa cells using MTT assay at 50 µm concentration. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
About the journal
JournalData powered by TypesetEuropean Journal of Organic Chemistry
PublisherData powered by TypesetWiley-VCH Verlag
Open AccessNo