Header menu link for other important links
Synthesis of (+)-centrolobine and its analogues by using acyl anion chemistry
Kasireddy Sudarshan,
Published in
Issue: 12
Pages: 2298 - 2302
A new route based on the use of acyl anion chemistry was developed for the synthesis of (+)-centrolobine and its analogues. Acid-catalyzed benzylic cation initiated cyclization was the key step in the stereoselective formation of the cis-2,6-disubstituted tetrahydropyran ring. The developed methodology was applied to the synthesis of (+)-centrolobine analogues containing electron-donating substituents in the aryl rings. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
About the journal
JournalEuropean Journal of Organic Chemistry
Open AccessNo