Header menu link for other important links
Synthesis and crystal structure of [2 + 2] calixsalens
Balasubramanian Viswanathan, Thirukkallam Kanthadai Varadarajan, Babu Varghese
Published in
Volume: 4
Issue: 16
Pages: 3044 - 3047
The synthesis and crystal structure of macrocyclic Schiff bases formed in a short reaction time from (1R,2R)-diammoniumcyclohexane mono-(+)-tartrate were investigated. Microwave irradiation of a mixture of bis-(hydroxyaldehydes) and chiral diamines in the presence of potassium carbonate afforded chiral macrocyclic tetraimines in moderate good yields. The structure of the [2+2] macrocycle was confirmed by both MALDI-TOF analysis and single-crystal XRD. The X-ray crystallographic analysis of the unsolved macrocycle Schiff base grown from a hexane-ethyl acetate solution confirmed the cyclic nature of the structure. The macrocycle stack in an eclipsed manner along the crystallographic a-axis, giving rise to infinite columns with macropores. The results show that the crystal structure of the macrocycles resembles that of calixarene and exhibits columnar staking in the solid state.
About the journal
JournalOrganic and Biomolecular Chemistry
Open AccessNo
Concepts (11)
  •  related image
    Crystal structure
  •  related image
  •  related image
  •  related image
  •  related image
    Synthesis (chemical)
  •  related image
    X ray diffraction
  •  related image
  •  related image
  •  related image
    Microwave irradiation
  •  related image
    Single-crystal xrd
  •  related image
    Aromatic compounds