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Surface Engineering Approaches for Controlling Biofilms and Wound Infections
Balaji Ramachandran,
Published in American Chemical Society
2019
Volume: 1323
   
Pages: 101 - 123
Abstract
Bacterial infection and biofilm formation are serious concerns in the wound healing process and with biomedical implants and devices. Different methods for engineering of surfaces have been studied over the years to mitigate biofilm formation. The major factors controlling biofilm formation are environmental, material, and bacterial properties. Out of these, engineering of the material surface is the most viable option for improving the antibacterial activity and controlling implant-related biofilm infections. These surface engineering strategies focus on altering physicochemical properties of the material surface, developing antiadhesive surfaces, coating with bioactive organic and inorganic molecules, and adding antimicrobial moieties to inhibit bacterial adhesion or express bacteriostatic or bactericidal effects. This chapter discusses the mechanism of biofilm formation and the surface engineering approaches applied to prevent biofilms. © 2019 American Chemical Society. All rights reserved.
About the journal
JournalData powered by TypesetACS Symposium Series
PublisherData powered by TypesetAmerican Chemical Society
ISSN00976156
Open AccessNo
Concepts (11)
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    Physicochemical properties
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    Surface properties
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    ANTI-ADHESIVE SURFACES
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    Anti-bacterial activity
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    Bacterial infections
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    BACTERICIDAL EFFECTS
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    Biomedical implants
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    INORGANIC MOLECULES
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    Surface engineering
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    WOUND HEALING PROCESS
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    Biofilms