Glass fiber reinforced gypsum (GFRG) wall panel is made essentially of gypsum plaster reinforced with glass fibers. The panels are hollow and can be used as load bearing walls. The hollow cores inside the walls can be filled with in-situ plain or reinforced concrete. This paper presents guidelines for the use of GFRG wall panel as a lateral load resisting component in buildings based on a numerical analysis procedure to arrive at its capacity estimation under axial compression, compression with inplane bending and shear. Variation of buckling load of unfilled GFRG wall panels for various widths is reported. The axial load carrying capacity of 1.02 m wide and 2.85 m high wall panel, obtained from the numerical analysis and the test results are comparable for this load case. While assessing the axial load capacity for design under compression, a minimum possible eccentricity (causing out-ofplane bending) is accounted for. An engineering model is proposed to assess the strength of unfilled and concrete filled GFRG wall panels in multi-storied building system subjected to lateral load such as earthquake.