In this paper, finite element simulations of spherical indentation of Nickel thin film on Steel-4340 are studied for single and multiple cycle of indentation as well. The objective was to understand the mechanics of coated systems, from load-displacement (P-h) curves, stress distribution in the film and the effect of substrate yield strength on the indentation response. The loading portion of P-h curve showed displacement bursts and the reason for this is investigated. A transition in the deformation behavior of the film from Hertz-type to flexure was observed for a normalized indentation depth of h/tf≈0.2. The influence of coating-substrate properties on P-h curve is also investigated for different h/tf ratios and yield strains. Attempts are also made to explore the possibility of understanding the creep-fatigue behavior of coated specimen subjected to cyclic indentation at room temperature from Indentation depth v/s time, Indentation depth v/s number of cycles and Plastic dissipation energy v/s number of cycles curve. Copyright © 2011 by ASME.