Header menu link for other important links
X
Ruthenium(II)-Catalyzed C−H Activation/Annulation of Aromatic Hydroxamic Acid Esters with Enamides Leading to Aminal Motifs
Dana S., Sureshbabu P., Giri C.K.,
Published in Wiley Online Library
2021
Volume: 2021
   
Issue: 9
Pages: 1385 - 1389
Abstract
Hydroxamic acid ester directed C(sp2)−H activation/annulation strategy has been reported employing electron-rich enamides under Ru(II)-catalysis to access aminal frameworks. Both N-vinyl acetamide and N-vinyl formamide delivered aminals bearing dihydroisoquinolinone motif in good yields. Under modified reaction conditions, vinyl acetate bestowed the selective formation of 3,4-unsubstituted isoquinolones. The protocol operates under mild conditions, where the C−H ruthenation step is reversible and apparently not the rate-determining step. © 2021 Wiley-VCH GmbH
About the journal
JournalData powered by TypesetEuropean Journal of Organic Chemistry
PublisherData powered by TypesetWiley Online Library
Open AccessNo