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Pseudo-CT image synthesis from Ultrasound images for potential use in Brachytherapy treatment planning - Initial results
B. Anila Satheesh, S. Arvind, R.R. Jeba Karunya, S. Ebenezer Suman Babu, T.S. Ram,
Published in Institute of Electrical and Electronics Engineers Inc.
Volume: 2021-December
Pages: 897 - 900
The most common means of treating a cancerous tumor is using radiation therapy that involves a combination of both external and internal radiation treatments. To aid the clinician to plan for the treatment, image-guided radiotherapy is used, in which computed tomography (CT) images are acquired multiple times during treatment. This puts the patient at unnecessary risk of additional radiation exposure. Simulating pseudo-CT scans have been proposed as an alternative to acquiring CT scans, thereby reducing the risks related to radiation exposure. In this study, we propose a methodology in which pseudo-CT images can be simulated from the pre-radiotherapy CT and ultrasound and pre-brachytherapy ultrasound images. The primary step in this is the registration between pre-radiotherapy and pre-brachytherapy ultrasound images. In this study, the performance of the demons deformable registration algorithm and mid-space independent image registration algorithm on ultrasound images of a cervical cancer patient are evaluated. The resultant deformation field obtained from the registration step is used to simulate the pseudo-CT image, which is then compared with the ground-truth CT image. The results show very little variability in the similarity metrics between the algorithms, indicating the feasibility of the proposed methodology. © 2021 IEEE.
About the journal
JournalIEEE Region 10 Annual International Conference, Proceedings/TENCON
PublisherInstitute of Electrical and Electronics Engineers Inc.