The International Symposia on Process Systems Engineering (PSE) have been a triennial tradition since 1982. The series was arranged by the International Organization for Process Systems Engineering with representation from the Asia Pacific Confederation of Chemical Engineering, the European Federation of Chemical Engineering, and the Inter-American Confederation of Chemical Engineering. It has proved to be an attractive global platform for the PSE academics, researchers, and practitioners from all corners of the world for sharing advances in PSE education, research, and application. PSE-2012, the 11th in the series, was held in the global village of Singapore during July 15–19, 2012.