The steady nonsimilar compressible laminar boundary-layer flow over a yawed infinite circular cylinder with nonuniform slot injection (suction) has been studied up to the point of separation. The finite discontinuities arising at the leading and trailing edges of the slot for the uniform slot injection (suction) are removed by choosing appropriate nonuniform mass transfer distributions in the slot. The difficulties arising at the starting point of the streamwise co-ordinate, at the edges of the slot and at the point of separation are overcome by applying the method of quasilinear implicit finite difference scheme with an appropriate selection of finer step size along the streamwise direction. It is found that the nonuniform slot injection moves the point of separation downstream but the nonuniform slot suction has the reverse effect. The increase of Mach number shifts the point of separation upstream due to the adverse pressure gradient. The increase of total enthalpy at the wall causes the separation to occur earlier while cooling delays it. The yaw angle has very little effect on the location of the point of separation.