In molecular self-assembly,molecules put themselves together in a predefined way by decoding the information already coded/stored in the molecules. Suitably selected chemical components are simply combined in a single-pot under proper environment. As a consequence, the participating components arrange themselves in a three-dimensional array. This work describes the philosophical approaches on the making of self-assembled coordination cages utilizing building blocks like palladium(II) and organic ligands. An exotic molecule of five-fold symmetry is considered as a particular example to describe the phenomenon. © 2018, Indian Academy of Sciences.