The output of a Wheatstone bridge with only a single active resistive sensor is inherently nonlinear. A generalized feedback compensation scheme is presented in this paper that provides a linear output for a Wheatstone bridge with only a single active resistive sensor, even for large variations in the resistance of the sensor. Simulation studies and experimental verifications establish the efficacy of the proposed linearization technique. The proposed method is best suited for single active resistive sensors involving Resistive Temperature Devices (RTD) and piezo-resistive type sensors possessing large range of variation.