Torsional response of buildings is attributed to poor structural configurations in plan, which arises due to two factors – torsional eccentricity and torsional flexibility. Usually, building codes address effects due to the former. This study examines both of these effects. Buildings with torsional eccentricity (e.g., those with large eccentricity) and with torsional flexibility (those with torsional mode as a fundamental mode) demand large deformations of vertical elements resisting lateral loads, especially those along the building perimeter in plan. Lateral-torsional responses are studied of unsymmetrical buildings through elastic and inelastic analyses using idealised single-storey building models (with two degrees of freedom). Displacement demands on vertical elements distributed in plan are non-uniform and sensitive to characteristics of both structure and earthquake ground motion. Limits are proposed to mitigate lateral-torsional effects, which guides in proportioning vertical elements and restricts amplification of lateral displacement in them and to avoid torsional mode as the first mode. Nonlinear static and dynamic analyses of multi-storey buildings are used to validate the limits proposed. Copyright © 2021 Techno-Press, Ltd.