Header menu link for other important links
X
Halogen-bonded iodonium ion catalysis: A route to α-hydroxy ketones: Via domino oxidations of secondary alcohols and aliphatic C-H bonds with high selectivity and control
Somraj Guha, Imran Kazi, Pranamita Mukherjee,
Published in Royal Society of Chemistry
2017
PMID: 28933462
Volume: 53
   
Issue: 79
Pages: 10942 - 10945
Abstract
A domino synthesis of α-hydroxy ketones has been developed from benzylic secondary alcohols employing catalytic iodonium ions stabilized by DMSO. The reaction proceeds through an unprecedented sequential oxidation of alcohols to ketone and its α-hydroxylation in a controlled manner. The spectroscopic evidence establishes the possibility of formation of a stable halogen-bonded adduct between DMSO and iodonium ions. © 2017 The Royal Society of Chemistry.
About the journal
JournalData powered by TypesetChemical Communications
PublisherData powered by TypesetRoyal Society of Chemistry
ISSN13597345
Open AccessNo
Concepts (17)
  •  related image
    Alcohol derivative
  •  related image
    Dimethyl sulfoxide
  •  related image
    Halogen
  •  related image
    Iodine
  •  related image
    Ketone derivative
  •  related image
    Article
  •  related image
    Catalysis
  •  related image
    Catalyst
  •  related image
    Chemical bond
  •  related image
    Hydrogen bond
  •  related image
    Molecular stability
  •  related image
    Oxidation
  •  related image
    Quantum yield
  •  related image
    Reaction analysis
  •  related image
    Stereoselectivity
  •  related image
    Stereospecificity
  •  related image
    Synthesis