Header menu link for other important links
Enhancing the feasibility of many biotechnological processes through enzyme deactivation studies
R. Srinivas,
Published in
Volume: 21
Issue: 4
Pages: 363 - 369
Enzymes are deactivated by different ways to an inactive state, which is a major constraint in the development of biotechnological processes. Understanding the complex process of enzyme deactivation will be helpful in enhancing the feasibility of many biological processes. This paper mainly deals with the different ways by which enzymes are inactivated, which includes the role of thermodynamics in deactivation. Different models namely, unified deactivation theory, single exponential model, rapid equilibrium model, isozyme model and bacterial contamination model used to describe the complex deactivation processes are also discussed in this communication. The complete understanding of deactivation process is very essential in commercialization because enzyme activity and stability of the enzyme play a critical role in economics of biotechnological processes. Activity and stability of the enzyme are conflicting properties and trade-off between these factors must be considered in the selection and design of enzymes.
About the journal
JournalBioprocess Engineering
Open AccessNo
Concepts (9)
  •  related image
  •  related image
  •  related image
  •  related image
    Enzyme activity
  •  related image
    Enzyme inactivation
  •  related image
    Enzyme specificity
  •  related image
    Enzyme stability
  •  related image
    Priority journal
  •  related image