The directed sorting approach towards the synthesis of inorganic bead libraries building, based on matrix methods and adsorption in well plates, was discussed. The main advantages of the system are its simplicity, ease of preparation and low cost. The use of a multi-pipettor and corresponding analysis eliminates the need of commercial plotters routinely used in combinatorial chemistry which results in large cost savings. This technique highlights the importance of order of addition in optimization of catalytic activity or other catalytic figures of merit.