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Chemical composition, structural features, surface morphology and bioactivities of chitosan derivatives from lobster (Thenus unimaculatus) shells
Meivelu Moovendhan
Published in Elsevier B.V.
2019
PMID: 31176860
Volume: 135
   
Pages: 1237 - 1245
Abstract
The chemical composition, structural features and bioactivities of chitosan derivatives were studied and reported here. Chitin and chitosan was extracted by chemical methods and yield was recorded 35% and 41%, moisture and ash has showed 7.4, 0.73, 1.2 and 0.79% and Ca was recorded high level (590 ppm). The IR spectrum has showed NH primary and secondary amines, OH group and several sugar stretching. N-acetyl glucosamine (GlcNAc), H-2 proton of glucosamine (GlcN), Anomeric protons, H-1 [GlcN (H-1D), GlcNAc (H-1A)] were noticed in 1H NMR and anomeric, methyl carbon atoms in 13C NMR. Rough surface, irregular block, crystalline with cluster and porosity structure was noticed by SEM observation. Antioxidant effect has showed good and concentration depended in four antioxidant assays. The α-amylase and β-glucosidase enzyme inhibition effect of chitosan has showed promising and dose depend also anticoagulant potential. Chitosan could be used in pharmaceutical industry and tissue engineering. © 2019 Elsevier B.V.
About the journal
JournalData powered by TypesetInternational Journal of Biological Macromolecules
PublisherData powered by TypesetElsevier B.V.
ISSN01418130
Open AccessNo
Concepts (55)
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    Amine
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    Amylase
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    Anticoagulant agent
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    Antidiabetic agent
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    Antioxidant
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    BETA GLUCOSIDASE
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    Calcium
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    Carbon
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    Chitin
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    Chitosan
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    CHITOSAN DERIVATIVE
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    Glucosamine
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    Hydroxyl group
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    Methyl group
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    N acetylglucosamine
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    Sugar
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    ANIMAL SHELL
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    ANTICOAGULATION
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    Antidiabetic activity
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    Antioxidant activity
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    ANTIOXIDANT ASSAY
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    Article
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    Ash
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    Carbon nuclear magnetic resonance
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    Chemical composition
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    Concentration response
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    Controlled study
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    Drug activity
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    Drug isolation
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    Drug structure
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    Enzyme inhibition
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    Infrared spectroscopy
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    LOBSTER
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    Moisture
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    Morphology
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    Nonhuman
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    Physical chemistry
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    Porosity
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    Proton nuclear magnetic resonance
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    Scanning electron microscopy
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    Surface property
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    THENUS UNIMACULATUS
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    Tissue engineering
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    Animal
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    Chemical phenomena
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    Chemistry
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    NEPHROPIDAE
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    Nuclear magnetic resonance spectroscopy
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    Structure activity relation
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    Animals
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    Antioxidants
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    Magnetic resonance spectroscopy
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    NEPHROPIDAE
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    Spectroscopy, fourier transform infrared
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    Structure-activity relationship