A variety of aromatic, aliphatic and conjugated alcohols were transformed into the corresponding carboxylic acids and ketones with aq 70% t-BuOOH in the presence of catalytic amounts of bismuth(III) oxide. This method possesses a wide range of capabilities, does not involve cumbersome work-up, exhibits chemoselectivity and proceeds under ambient conditions. The resulting products are obtained in good yields within reasonable time. The overall method is green. © 2010 Georg Thieme Verlag Stuttgart New York.

Debashis Chakraborty

Ambient conditions

BI2O3

Catalytic amounts

Catalyzed oxidation

Chemo-selectivity

Good yield

T-BUOOH

TERT-BUTYLHYDROPEROXIDE

Bismuth

Carboxylic acids

Ketones

oxidation

Reaction rates

(2 METHOXYPHENYL)METHANOL

tert butyl hydroperoxide

unclassified drug

Alcohol oxidation

article

biotransformation

catalysis

chemical structure

conjugation

high performance liquid chromatography

hydroxylation

stoichiometry

synthesis

IIT Madras is a public technical and research university located in Chennai, Tamil Nadu. Founded in 1959, it is recognised as an Institute of National Importance.

IIT Madras has been ranked as the top engineering institute in India for four years in a row by the National Institutional Ranking Framework of the MHRD

It currently offers undergraduate, postgraduate and research degrees across 16 disciplines in Engineering, Sciences, Humanities and Management. About 596 faculty belonging to science and engineering departments and centres of the Institute are engaged in teaching, research and industrial consultancy.

IIT Madras

Synthesis

A variety of aromatic, aliphatic and conjugated aldehydes were transformed to the corresponding carboxylic acids with 70% t-BuOOH solution (water) in the presence of catalytic amounts of Bi2O3. This method possesses a wide range of capabilities, does not involve cumbersome work-up, exhibits chemoselectivity and proceeds under mild conditions. The resulting products are obtained in good yields within reasonable time. The overall method is green. © 2010 Elsevier Ltd. All rights reserved.

Tetrahedron Letters

Bi2O3-catalyzed oxidation of aldehydes with t-BuOOH

A variety of aromatic, aliphatic and conjugated aldehydes were converted to the corresponding carboxylic acid derivatives with 30% H2O 2 as the oxidant in the presence of catalytic amounts of AgNO 3. The method described has wide range of applicabilities, does not involve cumbersome work-up, exhibits chemoselectivity and proceeds under mild reaction conditions, and the resulting products are obtained in good yields within reasonable time. © 2009 Elsevier Ltd. All rights reserved.

Silver nitrate-catalyzed oxidation of aldehydes to carboxylic acids by H2O2

Aromatic aldehydes possessing a wide variety of substituents were smoothly converted to carboxylic acids in excellent yields by stoichiometric bismuth(III) nitrate pentahydrate in presence of aerial oxygen in a microwave-oven under solvent-free conditions. The method is environmentally benign being solvent-free, operationally simple, highly chemoselective, employing no cumbersome work-up procedures, having wide general applicability, short reaction times, mild reaction conditions, large scale-ups and very good yields. © 2008 Elsevier B.V. All rights reserved.

Catalysis Communications

Bismuth(III) nitrate pentahydrate: a stoichiometric reagent for microwave induced mild and highly efficient aerial oxidation of aromatic aldehydes under solvent-free conditions

European Journal of Organic Chemistry

Graphical Abstract: Eur. J. Org. Chem. 18/2007

Chemistry - A European Journal

Scope, Kinetics, and Mechanistic Aspects of Aerobic Oxidations Catalyzed by Ruthenium Supported on Alumina

Bismuth(III) oxide catalyzed oxidation of alcohols with tert-butyl hydroperoxide

Journal	Synthesis
ISSN	00397881
Open Access	No