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An Improved System for Quantitative Immunoassay Measurement in ImageQuant
Published in Institute of Electrical and Electronics Engineers Inc.
2018
Volume: 2018-October
   
Abstract
ImageQuant Analyzer is an affordable, compact lateral flow immunoassay (LFIA) based PoC diagnostic reader capable of fast quantitative evaluation of analyte concentration from a sample. In this paper, ImageQuant's evolved hardware and software algorithm is described. To validate improvements, TSH analyte from human sera samples were analyzed. Correlation plots between proposed measurements and a Gold Standard reference show superiority of our system (R = 0.96) in predicting TSH concentrations. Validation results for test trials within a single instrument and across instruments (intra-variability < 2 % and inter-variability < 5.5 %) also signify the merits of the newly improved algorithm. © 2018 IEEE.
About the journal
JournalData powered by TypesetProceedings of IEEE Sensors
PublisherData powered by TypesetInstitute of Electrical and Electronics Engineers Inc.
ISSN19300395
Open AccessNo
Concepts (7)
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    Immunology
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    DIAGNOSTIC INSTRUMENTATION
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    IMAGEQUANT
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    Immunoassay
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    LFIA
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    POINT-OF-CARE TESTING
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    Image enhancement