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An Imageless Ultrasound Device to Measure Local and Regional Arterial Stiffness
Published in Institute of Electrical and Electronics Engineers Inc.
2016
PMID: 25775498
Volume: 10
   
Issue: 1
Pages: 200 - 208
Abstract
Arterial stiffness (AS) has been shown to be an important marker for risk assessment of cardiovascular events. Local arterial stiffness (LAS) is conventionally measured by evaluating arterial distensibility at particular arterial sites through ultrasound imaging systems. Regional arterial stiffness (RAS) is generally obtained by evaluating carotid to femoral pulse wave velocity (cfPWV) through tonometric devices. RAS has a better prognostic value than LAS and cfPWV is considered as the gold standard of AS. Over the past few years our group has been developing ARTerial Stiffness Evaluation for Non-Invasive Screening (ARTSENS), an inexpensive and portable device to measure the LAS. It uses a single element ultrasound transducer to obtain A-Mode frames from the desired artery and is fully automated to enable a non-expert to perform measurements. In this work, we report an extension of ARTSENS to enable measurement of cfPWV that now makes it the only fully automatic device that can measure both LAS and RAS. In this paper, we provide a general review of the ARTSENS and compare it with other state-of-the-art AS measurement systems. cfPWV measurement using ARTSENS was cross-validated against SphygmoCor by successive measurements with both devices on 41 human subjects and excellent agreement between both devices was demonstrated (Coefficient of determination R2) = 0.70(p < 0.00001) and, limits of agreement (LoA) < 1.6 m/s). The inter-device correlation between ARTSENS and SphygmoCor was found to be better than other similar studies reported in the literature. © 2015 IEEE.
About the journal
JournalData powered by TypesetIEEE Transactions on Biomedical Circuits and Systems
PublisherData powered by TypesetInstitute of Electrical and Electronics Engineers Inc.
ISSN19324545
Open AccessNo
Concepts (31)
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    Acoustic wave velocity
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    Stiffness
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    Ultrasonic imaging
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    Ultrasonic transducers
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    Wave propagation
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    ARTERIAL DISTENSIBILITY
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    ARTERIAL STIFFNESS
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    CARDIOVASCULAR EVENT
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    Coefficient of determination
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    Measurement system
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    PULSE WAVE VELOCITY
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    ULTRASOUND IMAGING SYSTEMS
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    ULTRASOUND TRANSDUCERS
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    Risk assessment
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    Adult
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    ARTERIAL STIFFNESS
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    Devices
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    Diagnostic imaging
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    Equipment design
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    FEMORAL ARTERY
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    Human
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    MANOMETRY
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    PULSE WAVE
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    Signal processing
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    Young adult
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    FEMORAL ARTERY
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    Humans
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    MANOMETRY
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    PULSE WAVE ANALYSIS
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    Signal processing, computer-assisted
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    VASCULAR STIFFNESS