Increasing demand for electricity, depleting reservoirs of fossil fuels and increasing environmental concerns, call for efficient and clean utilization of available energy. Electrochemical technologies such as batteries, fuel cells and flow batteries are promising alternatives for such clean and efficient energy conversion. While extensive heuristics exist to guide the choice of technology, very little work has been done on development of systematic and rational frameworks to quantitatively benchmark the merits/demerits of potential technologies using a matrix of several factors. In this work, we describe a framework that addresses this gap with a focus on three technologies, viz, batteries, fuel cells and flow batteries. The proposed framework currently evaluates two factors: power and energy density. An algorithm that generates gravimetric and volumetric cost comparisons between secondary batteries, flow batteries and fuel cells is presented. Since the available chemistries are numerous, comparisons are made for the most promising current chemistries for each technology, namely, lithium ion battery, hydrogen PEM fuel cells and all vanadium redox flow battery. For a given application, the algorithm also identifies optimal designs for the corresponding technologies. Generalization of the framework for other factors such as reliability, lifespan, etc. and different chemistries (for each technology) will also be outlined. © 2017 Elsevier B.V.